Extensively drug-resistant typhoid in Pakistan

Updated: September 24, 2021


Original publication date: January 30, 2019

Current situation

There is an ongoing outbreak of extensively drug-resistant  typhoid fever in Pakistan that does not respond to most antibiotics. Cases were first reported in Hyderabad and the city of Karachi, but the outbreak has now spread to other parts of the country. Canada and several other countries have reported cases of extensively drug-resistant typhoid fever in travellers returning from Pakistan.

About typhoid

Typhoid fever is an illness that is caused by a type of Salmonella bacteria called Salmonella typhi. Extensively drug-resistant typhoid is resistant to at least five different antibiotic classes.

Typhoid fever can be spread to humans through:

All travellers to Pakistan are at risk of getting extensively drug-resistant typhoid fever.

If you are travelling to visit friends and relatives, you are at higher risk of getting typhoid fever than tourists and business travellers. Travellers visiting family and friends are more likely to eat local food and be exposed to untreated water, which puts them at a greater risk for food and water-borne diseases.


Consult a health care professional or visit a travel health clinic at least 6 weeks before you travel.

Before your trip

During your trip

Monitor your symptoms

Registration of Canadians Abroad

Sign up with the Registration of Canadians Abroad service to stay connected with the Government of Canada in case of an emergency abroad or an emergency at home.

Report a problem on this page
Please select all that apply:

Thank you for your help!

You will not receive a reply. For enquiries, please contact us.

Date modified: